Leonie Voorwerk

High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types

Daniel J. McGrail, P.G. Pilié, N.U. Rashid et al. · Annals of Oncology · 2021 · 1K citations · Full text

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial

Leonie Voorwerk, Maarten Slagter, Hugo M. Horlings et al. · Nature Medicine · 2019 · 854 citations

Tumor Immunology, Breast Oncology, Cancer Immunosurveillance +10

Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer

Dora Hammerl, John W.M. Martens, Mieke Timmermans et al. · Nature Communications · 2021 · 229 citations · Full text

Breast Oncology, Immunology, Immune Regulation +20

IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

Olga Blomberg, Lorenzo Spagnuolo, Hannah Garner et al. · Cancer Cell · 2022 · 192 citations · Full text

Cancer Immunosurveillance, Autoimmune Disease, Immunology +9

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Zuzana Kos, Elvire Roblin, Rim S. Kim et al. · npj Breast Cancer · 2020 · 190 citations · Full text