Concepedia

Author

Lorenzo Spagnuolo

University of FribourgORCID

Also Known As

L Spagnuolo, L. Spagnuolo, Lorenzo Spagnuolo

21

Publications

718

Citations

11

H-Index

20

Concepts

All Affiliations

University of FribourgUniversity of GenevaOncode InstituteThe Netherlands Cancer InstituteSan Raffaele University of Rome
LS

About

Lorenzo Spagnuolo is an author at University of Fribourg specializing in immunotherapy, immunology, and medicine.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

5

5

376

2

Immunology

5

5

376

3

Cell Biology

3

3

306

4

Engineering

1

1

58

5

Biomedical Engineering

1

1

58

Lorenzo Spagnuolo

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9

Publications

518

Citations

9

H-Index

YearCitations

IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

Olga Blomberg, Lorenzo Spagnuolo, Hannah Garner,

Cancer Cell

2022

192

TLR7-based cancer immunotherapy decreases intratumoral myeloid-derived suppressor cells and blocks their immunosuppressive function

Thibaud Spinetti, Lorenzo Spagnuolo, Inès Mottas,

OncoImmunology

2016

79

Amphiphilic nanoparticle delivery enhances the anticancer efficacy of a TLR7 ligand via local immune activation

Inès Mottas, Ahmet Bekdemir, Alessandra Cereghetti,

Biomaterials

2018

58

Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade

Chiara Secondini, Oriana Coquoz, Lorenzo Spagnuolo,

OncoImmunology

2017

56

Neoadjuvant immune checkpoint blockade triggers persistent and systemic T <sub>reg</sub> activation which blunts therapeutic efficacy against metastatic spread of breast tumors

Olga Blomberg, Kevin Kos, Lorenzo Spagnuolo,

OncoImmunology

2023

55

Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses

C. Hotz, Marina Treinies, Inès Mottas,

OncoImmunology

2016

35

CDC25A Protein Stability Represents a Previously Unrecognized Target of HER2 Signaling in Human Breast Cancer: Implication for a Potential Clinical Relevance in Trastuzumab Treatment

Emanuela Brunetto, Anna Maria Ferrara, Francesca Rampoldi,

Neoplasia

2013

19

LBA10 Critical role of eosinophils during response to immune checkpoint blockade in breast cancer and other cancer types

Leonie Voorwerk, Hannah Garner, Olga Blomberg,

Annals of Oncology

2020

12

HMGB1 promotes CXCL12‐dependent egress of murine B cells from Peyer's patches in homeostasis

Lorenzo Spagnuolo, Viola Puddinu, Noémie Boss,

European Journal of Immunology

2021

12

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