Geneviève Laflamme

Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131

Tomáš Cihlář, Adrian S. Ray, Constantine G. Boojamra et al. · Antimicrobial Agents and Chemotherapy · 2007 · 94 citations

Medicinal Chemistry, Gs-9148 Diphosphate, Biochemistry +15

Molecular Assessment of the Potential for Renal Drug Interactions between Tenofovir and HIV Protease Inhibitors

Tomáš Cihlář, Adrian S. Ray, Geneviève Laflamme et al. · Antiviral Therapy · 2007 · 91 citations

Common Respiratory Viruses in Lower Airways of Patients with Acute Hypersensitivity Pneumonitis

Azzeddine Dakhama, Richard G. Hegele, Geneviève Laflamme et al. · American Journal of Respiratory and Critical Care Medicine · 1999 · 84 citations

Asthma, Respiratory Virus Immunity, Inflammatory Lung Disease +17

Selective blockade of CD28 and not CTLA-4 with a single-chain Fv–α1-antitrypsin fusion antibody

Bernard Vanhove, Geneviève Laflamme, Flora Coulon et al. · Blood · 2003 · 68 citations

Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148

Richard L. Mackman, Adrian S. Ray, Hon C. Hui et al. · Bioorganic & Medicinal Chemistry · 2010 · 59 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8