Daniel D. De Carvalho

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

David Roulois, Helen Loo Yau, Rajat Singhania et al. · Cell · 2015 · 1.4K citations · Full text

Endogenous Transcripts, Oncogenic Agent, Colorectal Cancer +10

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

Xiaojing Yang, Han Han, Daniel D. De Carvalho et al. · Cancer Cell · 2014 · 1.2K citations · Full text

Chromatin, Systems Biology, Epigenetic Change +8

Sensitive tumour detection and classification using plasma cell-free DNA methylomes

Shu Yi Shen, Rajat Singhania, Gordon Fehringer et al. · Nature · 2018 · 974 citations · Full text

Cancer Research, Chromatin, Sensitive Tumour Detection +11

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

Wanqiang Sheng, Martin W. LaFleur, Thao H. Nguyen et al. · Cell · 2018 · 659 citations

Tumor Immunity, Immune Checkpoint Inhibitor, Tumor Suppressor +3

TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure

Ankur Chakravarthy, Lubaba Khan, Nathan Peter Bensler et al. · Nature Communications · 2018 · 637 citations · Full text

Immunology, Cancer-associated Fibroblasts, Immunotherapy +17