Shu Yi Shen

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

David Roulois, Helen Loo Yau, Rajat Singhania et al. · Cell · 2015 · 1.4K citations · Full text

Endogenous Transcripts, Oncogenic Agent, Colorectal Cancer +10

Sensitive tumour detection and classification using plasma cell-free DNA methylomes

Shu Yi Shen, Rajat Singhania, Gordon Fehringer et al. · Nature · 2018 · 974 citations · Full text

Cancer Research, Chromatin, Sensitive Tumour Detection +11

Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes

Pier Vitale Nuzzo, Jacob E. Berchuck, Keegan Korthauer et al. · Nature Medicine · 2020 · 277 citations · Full text

Urology, Genitourinary Cancer, Kidney Research +8

Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes

Farshad Nassiri, Ankur Chakravarthy, Shengrui Feng et al. · Nature Medicine · 2020 · 260 citations · Full text

Chromatin, Neuro-oncology, Medicine +11

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2

Satoshi Inoue, Wanda Y. Li, Alan Tseng et al. · Cancer Cell · 2016 · 197 citations · Full text

Genome Instability, Dna Damage, Alters Dna Repair +10