Synthesis, in Vitro, and in Cell Studies of a New Series of [Indoline-3,2′-thiazolidine]-Based p53 Modulators

Alessia Bertamino, Maria Soprano, Simona Musella, +12

Journal of Medicinal Chemistry

Chemoprevention StrategyP53 ProteinNew SeriesPharmaceutical ChemistryTumor Biology +15

Identification of the Spiro(oxindole-3,3′-thiazolidine)-Based Derivatives as Potential p53 Activity Modulators

Isabel Gómez‐Monterrey, Alessia Bertamino, Amalia Porta, +14

Journal of Medicinal Chemistry

Bioorganic ChemistryPharmacotherapyChemical BiologyPharmaceutical ChemistryRedox Biology +17

Human Glioblastoma Multiforme: p53 Reactivation by a Novel MDM2 Inhibitor

Barbara Costa, S Bendinelli, P Gabelloni, +12

PLoS ONE

Chemoprevention StrategyIsa27 AdministrationP53 AvailabilityHigh-grade GliomasCancer Biology +14

Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines

Marina Sala, Adele Chimento, Carmela Saturnino, +11

Bioorganic & Medicinal Chemistry Letters

Cytotoxic Activity EvaluationBiochemistryMedicine2,3-Thiazolidin-4-one DerivativesAnti-cancer Agent +3

Fast Profiling of Natural Pigments in Different Spirulina (Arthrospira platensis) Dietary Supplements by DI-FT-ICR and Evaluation of their Antioxidant Potential by Pre-Column DPPH-UHPLC Assay

Eduardo Sommella, Giulio Maria Conte, Emanuela Salviati, +7

Molecules

Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification

Daniela Carbone, Vincenzo Vestuto, Maria Rosalia Ferraro, +15

European Journal of Medicinal Chemistry

Drug TargetBiochemistryMedicineNortopsentin-inspired LibraryMetabolomics-assisted Discovery +8

Characterization of New TRPM8 Modulators in Pain Perception

Carmen De, Claudia Cristiano, Carmen Avagliano, +8

International Journal of Molecular Sciences

Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines

Adele Chimento, Marina Sala, Isabel Gómez‐Monterrey, +13

Bioorganic & Medicinal Chemistry Letters

Biological ActivityBiochemistryMedicineNatural SciencesPharmacological Agent +4

Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity

Alessia Bertamino, Nunzio Iraci, Carmine Ostacolo, +15

Journal of Medicinal Chemistry

Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators

Alessia Bertamino, Carmine Ostacolo, Paolo Ambrosino, +13

Journal of Medicinal Chemistry

Channel ModulatorsPain MedicineSynaptic TransmissionMolecular PainPharmacotherapy +23