Susan M. Medghalchi

Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

Susan M. Medghalchi · Human Molecular Genetics · 2001 · 305 citations

Developmental Biology, Genetics, Embryonic Viability +14

Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.

Weibo Zhou, P. Jeanette Simpson, Jill M. McFadden et al. · PubMed · 2003 · 218 citations

Apoptosis, Cell Death, S Phase +17

Novel Upf2p Orthologues Suggest a Functional Link between Translation Initiation and Nonsense Surveillance Complexes

Joshua T. Mendell, Susan M. Medghalchi, Ross Lake et al. · Molecular and Cellular Biology · 2000 · 166 citations · Full text

Translation Studies, Engineering, Molecular Biology +19

Fatty Acid Synthase Inhibition Activates AMP-Activated Protein Kinase in SKOV3 Human Ovarian Cancer Cells

Weibo Zhou, Wan Fang Han, Leslie E. Landree et al. · Cancer Research · 2007 · 156 citations · Full text

Mammalian orthologues of a yeast regulator of nonsense transcript stability.

Haley A. Perlick, Susan M. Medghalchi, Forrest Spencer et al. · Proceedings of the National Academy of Sciences · 1996 · 133 citations

Engineering, Genetics, Nonsense Transcript Stability +18