Craig A. Townsend

Reduced Food Intake and Body Weight in Mice Treated with Fatty Acid Synthase Inhibitors

Thomas M. Loftus, Donna E. Jaworsky, Gojeb L. Frehywot et al. · Science · 2000 · 1K citations

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

Gregory L. Challis, Jacques Ravel, Craig A. Townsend · Chemistry & Biology · 2000 · 805 citations · Full text

Biochemistry, Biomolecular Structure Prediction, Protein Folding +12

Synthesis and antitumor activity of an inhibitor of fatty acid synthase

Francis P. Kuhajda, Ellen S. Pizer, Ji Nong Li et al. · Proceedings of the National Academy of Sciences · 2000 · 562 citations

Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts.

Ellen S. Pizer, Jagan N. Thupari, Wan Fang Han et al. · PubMed · 2000 · 369 citations

Breast Oncology, Chemoprevention Strategy, Fatty-acid Synthase Inhibition +17

Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.

Weibo Zhou, P. Jeanette Simpson, Jill M. McFadden et al. · PubMed · 2003 · 218 citations

Apoptosis, Cell Death, S Phase +17