Karl S. A. Vallin

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 529 citations

Medicine, Cancer Biology, Oncology +4

High-Speed Heck Reactions in Ionic Liquid with Controlled Microwave Heating

Karl S. A. Vallin, Per Emilsson, Mats Larhed et al. · The Journal of Organic Chemistry · 2002 · 164 citations

Natural Sciences, Chemistry, Catalysis +9

Validation and development of MTH1 inhibitors for treatment of cancer

Ulrika Warpman Berglund, Kumar Sanjiv, Helge Gad et al. · Annals of Oncology · 2016 · 145 citations · Full text

Medicine, Oncology, Pharmacology +7

Aromatic Lipoxin A₄and Lipoxin B₄Analogues Display Potent Biological Activities

Timothy P. O’Sullivan, Karl S. A. Vallin, Syed Tasadaque Ali Shah et al. · Journal of Medicinal Chemistry · 2007 · 106 citations

Medicine, Biochemistry, Pharmacology +12

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Nadilly Bonagas, Nina Gustafsson, Martin Henriksson et al. · Nature Cancer · 2022 · 105 citations · Full text

Life Sciences, Molecular Biology, Oncology +16