Emily E. Reid

A New Class of Antibody–Drug Conjugates with Potent DNA Alkylating Activity

Michael L. Miller, Nathan Fishkin, Wěi Li et al. · Molecular Cancer Therapeutics · 2016 · 101 citations

Pharmacy, Medicinal Chemistry, Oncology +17

Synthesis and Biological Evaluation of Antibody Conjugates of Phosphate Prodrugs of Cytotoxic DNA Alkylators for the Targeted Treatment of Cancer

Robert Y. Zhao, Hans K. Erickson, Barbara A. Leece et al. · Journal of Medicinal Chemistry · 2011 · 62 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody–Drug Conjugates (ADCs)

Michael L. Miller, Manami Shizuka, Alan Wilhelm et al. · Molecular Cancer Therapeutics · 2018 · 55 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14

Optimizing Lysosomal Activation of Antibody–Drug Conjugates (ADCs) by Incorporation of Novel Cleavable Dipeptide Linkers

Paulin Salomon, Emily E. Reid, Katie E. Archer et al. · Molecular Pharmaceutics · 2019 · 51 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody–Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation

Chen Bai, Emily E. Reid, Alan Wilhelm et al. · Bioconjugate Chemistry · 2019 · 34 citations · Full text

Pharmacy, Oncology, Pharmacology +17