Concepedia

Author

Manami Shizuka

ImmunoGen (United States)

Also Known As

M. Shizuka, Manami Shizuka

26

Publications

289

Citations

8

H-Index

11

Concepts

All Affiliations

ImmunoGen (United States)Boston College
MS

About

Manami Shizuka is an author at ImmunoGen (United States) specializing in natural sciences, organic chemistry, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Natural Sciences

2

2

42

2

Biochemistry

2

2

42

3

Engineering

1

1

28

4

Chemical Biology

1

1

14

5

Chemistry

1

1

28

Manami Shizuka

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8

Publications

269

Citations

8

H-Index

YearCitations

Catalytic Enantioselective Hosomi–Sakurai Conjugate Allylation of Cyclic Unsaturated Ketoesters

Manami Shizuka, Marc L. Snapper

Angewandte Chemie International Edition

2008

88

A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody–Drug Conjugates (ADCs)

Michael L. Miller, Manami Shizuka, Alan Wilhelm,

Molecular Cancer Therapeutics

2018

53

Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody–Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation

Chen Bai, Emily E. Reid, Alan Wilhelm,

Bioconjugate Chemistry

2019

30

Catalytic Enantioselective Hosomi–Sakurai Conjugate Allylation of Cyclic Unsaturated Ketoesters

Manami Shizuka, Marc L. Snapper

Angewandte Chemie

2008

28

Discovery of <b>MK-4688</b> : an Efficient Inhibitor of the HDM2–p53 Protein–Protein Interaction

Michael H. Reutershan, Michelle R. Machacek, Michael D. Altman,

Journal of Medicinal Chemistry

2021

23

Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody–Drug Conjugates (ADCs)

Emily E. Reid, Katie E. Archer, Manami Shizuka,

ACS Medicinal Chemistry Letters

2019

20

Synthesis of Isoprostanyl Phosphatidylcholine and Isoprostanyl Phosphatidylethanolamine

Manami Shizuka, Thomas O. Schrader, Marc L. Snapper

The Journal of Organic Chemistry

2006

14

Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody–Drug Conjugates (ADCs)

Katie E. Archer, Emily E. Reid, Manami Shizuka,

ACS Medicinal Chemistry Letters

2019

13

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