Concepedia

Alan Wilhelm

AW

13

Publications

575

Citations

11

H-Index

2013

Active since

Affiliations

ImmunoGen (United States)(Current)

Alan Wilhelm is an author at ImmunoGen (United States) specializing in medicine, pharmacology, and biomolecular engineering.

Top concepts

Publications per year

2013–2023

13

Publications

13

A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells

Yelena Kovtun, Gregory E. Jones, Sharlene Adams et al. · Blood Advances · 2018 · 174 citations · Full text

A New Class of Antibody–Drug Conjugates with Potent DNA Alkylating Activity

Michael L. Miller, Nathan Fishkin, Wěi Li et al. · Molecular Cancer Therapeutics · 2016 · 100 citations

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A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody–Drug Conjugates (ADCs)

Michael L. Miller, Manami Shizuka, Alan Wilhelm et al. · Molecular Cancer Therapeutics · 2018 · 53 citations · Full text

Optimizing Lysosomal Activation of Antibody–Drug Conjugates (ADCs) by Incorporation of Novel Cleavable Dipeptide Linkers

Paulin Salomon, Emily E. Reid, Katie E. Archer et al. · Molecular Pharmaceutics · 2019 · 48 citations · Full text

A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation

Nicholas C. Yoder, Chen Bai, Daniel Tavares et al. · Molecular Pharmaceutics · 2019 · 36 citations

, , +18

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