Concepedia

Barbara A. Leece

BA

13

Publications

1.6K

Citations

13

H-Index

1988

Active since

Affiliations

ImmunoGen (United States)(Current)

Stony Brook University

State University of New York

DuPont (United States)

Barbara A. Leece is an author at ImmunoGen (United States) specializing in medicine, pharmacology, and drug discovery.

Top concepts

Publications per year

1988–2015

13

Publications

13

Antibody-Drug Conjugates Designed to Eradicate Tumors with Homogeneous and Heterogeneous Expression of the Target Antigen

Yelena Kovtun, Charlene A. Audette, Yumei Ye et al. · Cancer Research · 2006 · 466 citations · Full text

Semisynthetic Maytansine Analogues for the Targeted Treatment of Cancer

Wayne C. Widdison, Sharon Wilhelm, Emily E. Cavanagh et al. · Journal of Medicinal Chemistry · 2006 · 311 citations

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Disulfide-Linked Antibody−Maytansinoid Conjugates: Optimization of In Vivo Activity by Varying the Steric Hindrance at Carbon Atoms Adjacent to the Disulfide Linkage

Brenda Kellogg, Lisa M. Garrett, Yelena Kovtun et al. · Bioconjugate Chemistry · 2011 · 209 citations

, , +21

Synthesis and Evaluation of Hydrophilic Linkers for Antibody–Maytansinoid Conjugates

Robert Y. Zhao, Sharon Wilhelm, Charlene A. Audette et al. · Journal of Medicinal Chemistry · 2011 · 201 citations

, , +14

Tumor-Specific Novel Taxoid−Monoclonal Antibody Conjugates

Iwao Ojima, X. Ben Wu, Christopher P. Borella et al. · Journal of Medicinal Chemistry · 2002 · 112 citations

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