Concepedia

Wayne C. Widdison

WC

Statistics

Publications

22

Citations

2.7K

H-Index

19

Active since

1987

Affiliations

ImmunoGen (United States)(Current)

Johnson & Johnson (United States)

Janssen (United States)

Wayne C. Widdison is an author at ImmunoGen (United States) specializing in pharmacology, medicine, and drug discovery.

ORCID

Top concepts

Publications per year

1987–2020

22

Publications

22

Antibody-Maytansinoid Conjugates Are Activated in Targeted Cancer Cells by Lysosomal Degradation and Linker-Dependent Intracellular Processing

Hans K. Erickson, Peter U. Park, Wayne C. Widdison et al. · Cancer Research · 2006 · 566 citations · Full text

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Semisynthetic Maytansine Analogues for the Targeted Treatment of Cancer

Wayne C. Widdison, Sharon Wilhelm, Emily E. Cavanagh et al. · Journal of Medicinal Chemistry · 2006 · 311 citations

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Antibody-Maytansinoid Conjugates Designed to Bypass Multidrug Resistance

Yelena Kovtun, Charlene A. Audette, Michele Mayo et al. · Cancer Research · 2010 · 254 citations

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Tumor Delivery and In Vivo Processing of Disulfide-Linked and Thioether-Linked Antibody−Maytansinoid Conjugates

Hans K. Erickson, Wayne C. Widdison, Michele Mayo et al. · Bioconjugate Chemistry · 2009 · 238 citations

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Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules

Manu Lopus, Emin Oroudjev, Leslie Wilson et al. · Molecular Cancer Therapeutics · 2010 · 221 citations · Full text

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