Concepedia

Wayne C. Widdison

WC

Statistics

Publications

22

Citations

2.7K

H-Index

19

Active since

1987

Affiliations

ImmunoGen (United States)(Current)

Johnson & Johnson (United States)

Janssen (United States)

Wayne C. Widdison is an author at ImmunoGen (United States) specializing in antibody-drug conjugates, antibody conjugates, and pharmacy.

ORCID

Publications per year

1987–2020

22

Publications

22

Antibody-Maytansinoid Conjugates Are Activated in Targeted Cancer Cells by Lysosomal Degradation and Linker-Dependent Intracellular Processing

Hans K. Erickson, Peter U. Park, Wayne C. Widdison et al. · Cancer Research · 2006 · 574 citations · Full text

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Semisynthetic Maytansine Analogues for the Targeted Treatment of Cancer

Wayne C. Widdison, Sharon Wilhelm, Emily E. Cavanagh et al. · Journal of Medicinal Chemistry · 2006 · 311 citations

, , +14

Antibody-Maytansinoid Conjugates Designed to Bypass Multidrug Resistance

Yelena Kovtun, Charlene A. Audette, Michele Mayo et al. · Cancer Research · 2010 · 259 citations

, , +16

Tumor Delivery and In Vivo Processing of Disulfide-Linked and Thioether-Linked Antibody−Maytansinoid Conjugates

Hans K. Erickson, Wayne C. Widdison, Michele Mayo et al. · Bioconjugate Chemistry · 2009 · 240 citations

, , +17

Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules

Manu Lopus, Emin Oroudjev, Leslie Wilson et al. · Molecular Cancer Therapeutics · 2010 · 230 citations · Full text

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