Analyses of Polyphenols in Cacao Liquor, Cocoa, and Chocolate by Normal-Phase and Reversed-Phase HPLC

Midori Natsume, Naomi Osakabe, Megumi Yamagishi, +5

Bioscience Biotechnology and Biochemistry

The Antioxidative Substances in Cacao Liquor.

Naomi Osakabe, Megumi Yamagishi, Chiaki Sanbongi, +3

Journal of Nutritional Science and Vitaminology

Food ChemistryPolyphenolicsFood Bioactive CompoundMedicineFood Analysis +10

Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model

Megumi Yamagishi, Midori Natsume, Naomi Osakabe, +5

Cancer Letters

Chemoprevention StrategyOncogenic AgentMedicineLung CarcinogenesisCacao Liquor Proanthocyanidins +6

Effects of cacao liquor proanthocyanidins on PhIP-induced mutagenesis in vitro, and in vivo mammary and pancreatic tumorigenesis in female Sprague–Dawley rats

Megumi Yamagishi, Midori Natsume, Naomi Osakabe, +5

Cancer Letters

Food Bioactive CompoundChemoprevention StrategyMedicinePhip-induced MutagenesisFemale Sprague–dawley Rats +6

Ingestion of Proanthocyanidins Derived from Cacao Inhibits Diabetes-Induced Cataract Formation in Rats

Naomi Osakabe, Megumi Yamagishi, Midori Natsume, +2

Experimental Biology and Medicine

NutritionBiochemistryOphthalmologyMedicineNutraceutical Ingredient +12

Effects of Polyphenol Substances Derived from<i>Theobroma cacao</i>on Gastric Mucosal Lesion Induced by Ethanol

Naomi Osakabe, Chiaki Sanbongi, Megumi Yamagishi, +2

Bioscience Biotechnology and Biochemistry

Food ChemistryFood Bioactive CompoundBiochemistryGastrointestinal PharmacologyMedicine +11

Antimutagenic Activity of Cacao:  Inhibitory Effect of Cacao Liquor Polyphenols on the Mutagenic Action of Heterocyclic Amines

Megumi Yamagishi, Midori Natsume, Atsushi Nagaki, +5

Journal of Agricultural and Food Chemistry

Food ChemistryBiochemistryMedicineNutraceutical IngredientHeterocyclic Amines +13

Effects of Cacao Liquor Polyphenols on the Susceptibility of Low-density Lipoprotein to Oxidation in Hypercholesterolemic Rabbits

Naomi Osakabe, Midori Natsume, Toko Adachi, +5

Journal of Atherosclerosis and Thrombosis

Dose‐dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with <i>N</i>‐methyl‐<i>N′</i>‐nitro‐<i>N</i>‐nitrosoguanidine: Possible contribution of nitric oxide‐associated oxidative DNA damage

Kazushi Okazaki, Yuji Ishii, Yasuki Kitamura, +9

Cancer Science

Procyanidins in Theobroma cacao Reduce Plasma Cholesterol Levels in High Cholesterol-Fed Rats

Naomi Osakabe, Megumi Yamagishi

Journal of Clinical Biochemistry and Nutrition

Metabolic SyndromeNutritionPolyphenolicsOxysterolBiochemistry +13