Esther Sammler

LRRK2 kinase in Parkinson's disease

Dario R. Alessi, Esther Sammler · Science · 2018 · 345 citations · Full text

Mitophagy, Immunology, Pathology +19

The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human

Rafeeq Mir, Francesca Tonelli, Thomas Macartney et al. · Biochemical Journal · 2018 · 210 citations · Full text

Retromer Complex, Mitophagy, Molecular Neuroscience +13

Synaptic Imbalance, Stereotypies, and Impaired Social Interactions in Mice with Altered Neuroligin 2 Expression

Rochelle M. Hines, Long‐Jun Wu, Dustin J. Hines et al. · Journal of Neuroscience · 2008 · 176 citations · Full text

Affective Neuroscience, E/i Imbalance, Neurotransmission +22

Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils

Ying Fan, Andrew J.M. Howden, Adil R. Sarhan et al. · Biochemical Journal · 2017 · 176 citations · Full text

Mitophagy, Sporadic Parkinson, Immunology +20

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

Xingui Liu, Alexia F. Kalogeropulou, Sofia Domingos et al. · Journal of the American Chemical Society · 2022 · 152 citations · Full text