Thomas P. Graycar - Concepedia

Author

Thomas P. Graycar

Also Known As

T Graycar, T P Graycar, T. Graycar, T. P. Graycar, T.P. Graycar, THOMAS GRAYCAR, THOMAS P. GRAYCAR, Thomas Graycar, Thomas P. Graycar

Publications

1.6K

Citations

H-Index

Concepts

All Affiliations

University of Toronto Kimball International (United States)

About

Thomas P. Graycar is an author at University of Toronto specializing in natural sciences, biochemistry, and biotechnology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	7	7	544
2	Biochemistry	7	7	544
3	Medicine	5	5	364
4	Biomolecular Engineering	4	4	425
5	Engineering	3	3	224

Thomas P. Graycar

Publications

1.5K

Citations

H-Index

Page 1

	Year	Citations
Engineering an enzyme by site-directed mutagenesis to be resistant to chemical oxidation. David A. Estell, Thomas P. Graycar, James A. Wells Journal of Biological Chemistry	1985	336
Probing Steric and Hydrophobic Effects on Enzyme-Substrate Interactions by Protein Engineering David A. Estell, Thomas P. Graycar, Jonathan Miller, Science	1986	245
Designing substrate specificity by protein engineering of electrostatic interactions. J A Wells, David B. Powers, R. Bott, Proceedings of the National Academy of Sciences Protein ChemistryProtein AssemblyBiochemistryProtein FoldingNatural Sciences	1987	201
The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation. R. Bott, Mark Ultsch, Anthony A. Kossiakoff, Journal of Biological Chemistry	1988	178
Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering. J A Wells, Brian C. Cunningham, Thomas P. Graycar, Proceedings of the National Academy of Sciences EngineeringProtein AssemblyMolecular BiologySerine ProteasesAmino Acid Substitutions	1987	137
Importance of hydrogen-bond formation in stabilizing the transition state of subtilisin James A. Wells, Brian C. Cunningham, Thomas P. Graycar, Philosophical Transactions of the Royal Society of London Series A Mathematical and Physical Sciences	1986	133
Alteration of the specificity of subtilisin BPN' by site-directed mutagenesis in its S1 and S1' binding sites Pierre Bonneau, Thomas P. Graycar, David A. Estell, Journal of the American Chemical Society Chemical AnalysisAltmetric Attention ScoreMolecular BiologyBibliometricsMolecular Genetics	1991	59
Protein and solvent engineering of subtilisin BPN' in nearly anhydrous organic media Pramod P. Wangikar, Thomas P. Graycar, David A. Estell, Journal of the American Chemical Society EngineeringChemical AnalysisOrganic ChemistryChemistryChemical Biology	1993	58
Chemical Modification of Cysteine Mutants of Subtilisin <i>Bacillus lentus</i> Can Create Better Catalysts Than the Wild-Type Enzyme Per Berglund, Grace DeSantis, Michele R. Stabile, Journal of the American Chemical Society BacteriologyChemical ModificationAltmetric Attention ScoreChemical BiologyBacterial Pathogens	1997	39
Probing the specificity of the S1 binding site of M222 mutants of subtilisin B. lentus with boronic acid inhibitors Michele R. Stabile, Wei‐Shiang Lai, Grace DeSantis, Bioorganic & Medicinal Chemistry Letters BiochemistryM222 MutantsNatural SciencesMolecular BiologyBoronic Acid Inhibitors	1996	36

Page 1