David A. Estell

Cloning, sequencing, and secretion of Bacillus<i>amyloliquefaciens</i>subtillisin in<i>Bacillus subtilis</i>

James A. Wells, E Ferrari, Dennis J. Henner et al. · Nucleic Acids Research · 1983 · 355 citations · Full text

Engineering an enzyme by site-directed mutagenesis to be resistant to chemical oxidation.

David A. Estell, Thomas P. Graycar, James A. Wells · Journal of Biological Chemistry · 1985 · 336 citations · Full text

Synergistic antiviral and antiproliferative activities of Escherichia coli-derived human alpha, beta, and gamma interferons

Christine W. Czarniecki, C Fennie, David B. Powers et al. · Journal of Virology · 1984 · 252 citations · Full text

Immunology, Antiviral Drug, Immunotherapy +16

Probing Steric and Hydrophobic Effects on Enzyme-Substrate Interactions by Protein Engineering

David A. Estell, Thomas P. Graycar, Jonathan Miller et al. · Science · 1986 · 245 citations

Designing substrate specificity by protein engineering of electrostatic interactions.

J A Wells, David B. Powers, R. Bott et al. · Proceedings of the National Academy of Sciences · 1987 · 201 citations · Full text

Protein Chemistry, Protein Assembly, Biochemistry +13