Sophie Hallakou‐Bozec

Imeglimin Normalizes Glucose Tolerance and Insulin Sensitivity and Improves Mitochondrial Function in Liver of a High-Fat, High-Sucrose Diet Mice Model

Guillaume Vial, Marie‐Agnès Chauvin, Nadia Bendridi et al. · Diabetes · 2014 · 190 citations

Life Sciences, Nutritional Sciences, Pharmacology +17

Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration

Dominique Détaille, Guillaume Vial, Cécile Cottet-Rouselle et al. · Cell Death Discovery · 2016 · 95 citations · Full text

Life Sciences, Pharmacology, Physiology +17

Imeglimin amplifies glucose-stimulated insulin release from diabetic islets via a distinct mechanism of action

Sophie Hallakou‐Bozec, Micheline Kergoat, Pascale Fouqueray et al. · PLoS ONE · 2021 · 87 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17

Evaluation of PXL065 – deuterium-stabilized (R)-pioglitazone in patients with NASH: A phase II randomized placebo-controlled trial (DESTINY-1)

Stephen A. Harrison, Carole Thang, Sébastien Bolze et al. · Journal of Hepatology · 2023 · 85 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +4

Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis

Pascale Gluais Dagorn, Marc Foretz, Gregory R. Steinberg et al. · Hepatology Communications · 2021 · 77 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17