Sébastien Bolze

Imeglimin Normalizes Glucose Tolerance and Insulin Sensitivity and Improves Mitochondrial Function in Liver of a High-Fat, High-Sucrose Diet Mice Model

Guillaume Vial, Marie‐Agnès Chauvin, Nadia Bendridi et al. · Diabetes · 2014 · 187 citations

Immunology, Insulin Signaling, Oxidative Stress +20

Imeglimin increases glucose‐dependent insulin secretion and improves β‐cell function in patients with type 2 diabetes

Giovanni Pacini, Andrea Mari, Pascale Fouqueray et al. · Diabetes Obesity and Metabolism · 2015 · 99 citations · Full text

Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration

Dominique Détaille, Guillaume Vial, Anne‐Laure Borel et al. · Cell Death Discovery · 2016 · 95 citations · Full text

Mitophagy, Imeglimin Treatment, Apoptosis +22

Imeglimin amplifies glucose-stimulated insulin release from diabetic islets via a distinct mechanism of action

Sophie Hallakou‐Bozec, Micheline Kergoat, Pascale Fouqueray et al. · PLoS ONE · 2021 · 83 citations · Full text

Glycobiology, Glucose-stimulated Insulin Release, Insulin Signaling +21

Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis

Pascale Gluais Dagorn, Marc Foretz, Gregory R. Steinberg et al. · Hepatology Communications · 2021 · 72 citations · Full text