Kurt O. Johnson

Senolytics improve physical function and increase lifespan in old age

Ming Xu, Tamar Pirtskhalava, Joshua N. Farr et al. · Nature Medicine · 2018 · 2.2K citations

Education, Geriatric Medicine, Physiology +14

Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors

Yi Zhu, Tamar Tchkonia, Heike Fuhrmann‐Stroissnigg et al. · Aging Cell · 2015 · 1.1K citations · Full text

Medicine, Molecular Medicine, Pharmacology +16

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

Ming Xu, Tamar Tchkonia, Husheng Ding et al. · Proceedings of the National Academy of Sciences · 2015 · 892 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

Allyson K. Palmer, Ming Xu, Yi Zhu et al. · Aging Cell · 2019 · 669 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Targeting senescent cells enhances adipogenesis and metabolic function in old age

Ming Xu, Allyson K. Palmer, Husheng Ding et al. · eLife · 2015 · 590 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17