Fabrice Le Bœuf

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

Caroline J. Breitbach, James M. Burke, Derek J. Jonker et al. · Nature · 2011 · 539 citations

Molecular Virology, Viral Pathogenesis, Immunology +6

The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers

Kelley A. Parato, Caroline J. Breitbach, Fabrice Le Bœuf et al. · Molecular Therapy · 2011 · 300 citations · Full text

Targeting of Interferon-Beta to Produce a Specific, Multi-Mechanistic Oncolytic Vaccinia Virus

David H. Kirn, Yaohe Wang, Fabrice Le Bœuf et al. · PLoS Medicine · 2007 · 202 citations · Full text

Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity

Carolina S. Ilkow, Monique Marguerie, Cory Batenchuk et al. · Nature Medicine · 2015 · 163 citations · Full text

Oncolytic Virus Activity, Immunology, Reciprocal Cellular Cross-talk +8

Regulation of Vascular Endothelial Growth Factor Receptor 2-mediated Phosphorylation of Focal Adhesion Kinase by Heat Shock Protein 90 and Src Kinase Activities

Fabrice Le Bœuf, François Houle, Jacques Huot · Journal of Biological Chemistry · 2004 · 147 citations · Full text

Endothelial Cells, Pathology, Cell Growth +18