Hsi-Yu Yen

Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

Sebastian Mueller, Thomas Engleitner, Roman Maresch et al. · Nature · 2018 · 445 citations · Full text

Medicine, Molecular Genetics, Oncology +10

Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin

Elisa Espinet, Zuguang Gu, Charles D. Imbusch et al. · Cancer Discovery · 2020 · 130 citations · Full text

Medicine, Cancer Biology, Oncology +17

A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy

Georgios Kaissis, Sebastian Ziegelmayer, Fabian Lohöfer et al. · PLoS ONE · 2019 · 75 citations · Full text

Medicine, Biomedical Informatics, Oncology +17

Implementing cell-free DNA of pancreatic cancer patient–derived organoids for personalized oncology

Zahra Dantes, Hsi-Yu Yen, Nicole Pfarr et al. · JCI Insight · 2020 · 49 citations · Full text

Medicine, Molecular Biology, Oncology +17

Image-Based Molecular Phenotyping of Pancreatic Ductal Adenocarcinoma

Georgios Kaissis, Sebastian Ziegelmayer, Fabian Lohöfer et al. · Journal of Clinical Medicine · 2020 · 48 citations · Full text

Medicine, Oncology, Radiology +17