Dylan Alexander Carlin

Kinetic Characterization of 100 Glycoside Hydrolase Mutants Enables the Discovery of Structural Features Correlated with Kinetic Constants

Dylan Alexander Carlin, Ryan W. Caster, Xiaokang Wang et al. · PLoS ONE · 2016 · 52 citations · Full text

Engineering, Machine Learning, Novel Enzyme Catalysts +19

The live biotherapeutic SYNB1353 decreases plasma methionine via directed degradation in animal models and healthy volunteers

Mylène Perreault, Jillian Means, Erik Gerson et al. · Cell Host & Microbe · 2024 · 27 citations · Full text

Live Biotherapeutic Synb1353, Biochemistry, Medicine +13

Thermal stability and kinetic constants for 129 variants of a family 1 glycoside hydrolase reveal that enzyme activity and stability can be separately designed

Dylan Alexander Carlin, Siena Hapig-Ward, Bill Wayne Chan et al. · PLoS ONE · 2017 · 26 citations · Full text

Glycobiology, Molecular Biology, Kinetic Constants +16

Elucidating Substrate Promiscuity within the FabI Enzyme Family

Gabriel S. Freund, Terrence E. O’Brien, Logan Vinson et al. · ACS Chemical Biology · 2017 · 21 citations

Biosynthesis, Enzymology, Fabi Enzyme Family +13