Edmund V. Price

Correlating chemical sensitivity and basal gene expression reveals mechanism of action

Matthew G. Rees, Brinton Seashore‐Ludlow, Jaime H. Cheah et al. · Nature Chemical Biology · 2015 · 942 citations · Full text

Signal Transduction, Molecular Physiology, Chemical Sensitivity +10

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 893 citations

Cancer Research, Allosteric Inhibition, Signal Transduction +12

Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset

Brinton Seashore‐Ludlow, Matthew G. Rees, Jaime H. Cheah et al. · Cancer Discovery · 2015 · 844 citations · Full text

An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

Amrita Basu, Nicole E. Bodycombe, Jaime H. Cheah et al. · Cell · 2013 · 842 citations · Full text

Dual Allosteric Inhibition of SHP2 Phosphatase

Michelle Fodor, Edmund V. Price, Ping Wang et al. · ACS Chemical Biology · 2018 · 127 citations · Full text