Concepedia

Author

Pearl Tanaka

Sunesis (United States)

Also Known As

P. Tanaka, Pearl Tanaka

7

Publications

194

Citations

6

H-Index

20

Concepts

All Affiliations

Sunesis (United States)
PT

About

Pearl Tanaka is an author at Sunesis (United States) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

4

4

141

2

Natural Sciences

1

1

32

3

Social Sciences

1

1

47

4

Biochemistry

1

1

32

5

Biomolecular Engineering

1

1

29

Pearl Tanaka

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5

Publications

188

Citations

5

H-Index

YearCitations

Selective and Brain‐Permeable Polo‐like Kinase‐2 (Plk‐2) Inhibitors That Reduce α‐Synuclein Phosphorylation in Rat Brain

Danielle L. Aubele, Roy K. Hom, Marc Adler,

ChemMedChem

2013

47

In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain

M. Bergeron, Ruth Motter, Pearl Tanaka,

Neuroscience

2013

47

Discovery of 4-alkylamino-7-aryl-3-cyanoquinoline LRRK2 kinase inhibitors

Albert W. Garofalo, Marc Adler, Danielle L. Aubele,

Bioorganic & Medicinal Chemistry Letters

2013

33

Discovery of (<i>R</i>)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1<i>H</i>-pyrazolo[4,3-<i>c</i>]quinoline (ELND006) and (<i>R</i>)-4-Cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2<i>H</i>-pyrazolo[4,3-<i>c</i>]quinoline (ELND007): Metabolically Stable γ-Secretase Inhibitors that Selectively Inhibit the Production of Amyloid-β over Notch

Gary D. Probst, Danielle L. Aubele, Simeon Bowers,

Journal of Medicinal Chemistry

2013

32

Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors

Simeon Bowers, Anh P. Truong, Michael Ye,

Bioorganic & Medicinal Chemistry Letters

2013

29

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