Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Nicholas McGranahan, Rachel Rosenthal, Crispin T. Hiley, +218

Cell

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

Frederick Arce Vargas, Andrew J.S. Furness, Isabelle Solomon, +245

Immunity

Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

Francesca Chemi, Dominic G. Rothwell, Nicholas McGranahan, +31

Nature Medicine

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

Bruno M. Simões, Ciara O’Brien, Rachel Eyre, +22

Cell Reports

Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows

Rita Lampignano, Martin H. Neumann, Sabrina Weber, +28

Clinical Chemistry

cfDNA methylome profiling for detection and subtyping of small cell lung cancers

Francesca Chemi, Simon P. Pearce, Alexandra Clipson, +21

Nature Cancer

The T cell differentiation landscape is shaped by tumour mutations in lung cancer

Ehsan Ghorani, James L. Reading, Jake Y. Henry, +298

Nature Cancer

Somatic VariantTumor HeterogeneityMedicineTumour MutationsPathology +7

Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth

Stefania Catalano, Cinzia Giordano, Salvatore Panza, +9

Breast Cancer Research and Treatment

Novel MechanismBreast OncologyAromatase ExpressionMedicineCancer Growth +7

Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity

Cinzia Giordano, Francesca Chemi, Salvatore Panza, +14

Oncotarget

A cfDNA methylation-based tissue-of-origin classifier for cancers of unknown primary

Alicia‐Marie Conway, Simon P. Pearce, Alexandra Clipson, +14

Nature Communications