Tao Jiang

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 405 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Structure–activity Relationships +21

Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I

Tao Jiang, Kelli Kuhen, Karen C. Wolff et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 290 citations

Medicinal Chemistry, Biochemistry, Biological Evaluations +10

Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2

Tao Jiang, Kelli Kuhen, Karen C. Wolff et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 197 citations

Medicinal Chemistry, Biochemistry, Biological Evaluations +11

Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 1

Ha-Soon Choi, Zhicheng Wang, Wendy Richmond et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 66 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Pharmaceutical Science +7

Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2

Ha-Soon Choi, Zhicheng Wang, Wendy Richmond et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 55 citations

Combinatorial Chemistry, Medicinal Chemistry, Pharmaceutical Science +7