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Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 1

Ha-Soon Choi, Zhicheng Wang, Wendy Richmond, Xiaohui He, Kunyong Yang, Tao Jiang, Taebo Sim, Donald S. Karanewsky, Xiang-ju Gu, Vicki Zhou,

Bioorganic & Medicinal Chemistry Letters · 2006 · 66 citations · 24 references

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24

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

Duško llić, Yasuhide Furuta, S. Kanazawa et al. · Nature · 1995 · 1.8K citations

, , +16

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Michael D. Schaller, Cheryl A. Borgman, Bradley S. Cobb et al. · Proceedings of the National Academy of Sciences · 1992 · 1.4K citations

, , +17

Control of adhesion-dependent cell survival by focal adhesion kinase.

Steven M. Frisch, Kristiina Vuori, Erkki Ruoslahti et al. · The Journal of Cell Biology · 1996 · 1.1K citations · Full text

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Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

Jun‐Lin Guan, David Shalloway · Nature · 1992 · 833 citations

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Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.

Steven K. Hanks, Mihail CALALB, Marion C. Harper et al. · Proceedings of the National Academy of Sciences · 1992 · 825 citations

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