PD-1 blockade therapy promotes infiltration of tumor-attacking exhausted T cell clonotypes

Joji Nagasaki, Takashi Inozume, Nicolas Sax, +23

Cell Reports

Exit from germinal center to become quiescent memory B cells depends on metabolic reprograming and provision of a survival signal

Takeshi Inoue, Ryo Shinnakasu, Kawai Chie, +8

The Journal of Experimental Medicine

Immunological MemorySignal TransductionCell RegulationCell DivisionSurvival Signal +13

Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3

H. Tanaka, Akihiko Muto, Hiroki Shima, +12

Journal of Biological Chemistry

Histone ModificationsChromatinBlimp-1 GeneChromatin RemodelingMedicine +10

HLA Class I Analysis Provides Insight Into the Genetic and Epigenetic Background of Immune Evasion in Colorectal Cancer With High Microsatellite Instability

Masahito Kawazu, Toshihide Ueno, Koichi Saeki, +33

Gastroenterology

HistocompatibilityHlaImmune EvasionMedicineGenetics +10

Distinct immune cell dynamics correlate with the immunogenicity and reactogenicity of SARS-CoV-2 mRNA vaccine

Tomohiro Takano, Miwa Morikawa, Yu Adachi, +15

Cell Reports Medicine

Morphological study of acoustic liposomes using transmission electron microscopy

Tetsuya Kodama, Noriko Tomita, Sachiko Horie, +5

Journal of Electron Microscopy

Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients

Xiuyuan Lu, Yuki Hosono, Masamichi Nagae, +27

The Journal of Experimental Medicine

The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization

Ryo Ando, Hiroki Shima, Toru Tamahara, +12

Journal of Biological Chemistry

Systems BiologySignal TransductionMurine B CellsCell RegulationMultiple Sites +8

The mTOR-Bach2 Cascade Controls Cell Cycle and Class Switch Recombination during B Cell Differentiation

Toru Tamahara, Kyoko Ochiai, Akihiko Muto, +5

Molecular and Cellular Biology

Bach2 Promotes B Cell Receptor–Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors

Yuichi Miura, Mizuho Morooka, Nicolas Sax, +9

The Journal of Immunology