Masahiro Yonaga

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist

Shigeki Hibi, Koshi Ueno, Satoshi Nagato et al. · Journal of Medicinal Chemistry · 2012 · 177 citations

Synaptic Transmission, Pyridone Ring, Neurotransmitter +21

Stereochemistry of palytoxin. Part 4. Complete structure

J. K., William J. Christ, Jennifer M. Finan et al. · Journal of the American Chemical Society · 1982 · 130 citations

Chemical Measurement, Bioorganic Chemistry, Engineering +15

Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium.

Yasuhiro Funahashi, Naoko Hata Sugi, Taro Semba et al. · PubMed · 2002 · 102 citations

Pharmacotherapy, Cellular Physiology, Tumor Biology +20

Discovery of (1<i>R</i>,2<i>S</i>)-2-{[(2,4-Dimethylpyrimidin-5-yl)oxy]methyl}-2-(3-fluorophenyl)-<i>N</i>-(5-fluoropyridin-2-yl)cyclopropanecarboxamide (E2006): A Potent and Efficacious Oral Orexin Receptor Antagonist

Yu Yoshida, Yoshimitsu Naoe, Taro Terauchi et al. · Journal of Medicinal Chemistry · 2015 · 83 citations · Full text

Pharmacotherapy, Chemical Biology, Experimental Pharmacology +19

Chiral synthesis of (+)-eburnamine, (–)-eburnamenine, and (–)-eburnamonine

Seiichi Takano, Masahiro Yonaga, Masamichi Morimoto et al. · Journal of the Chemical Society Perkin Transactions 1 · 1985 · 55 citations

Diversity Oriented Synthesis, Bioorganic Chemistry, Engineering +12