Taro Semba

Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage

Yuji Yamamoto, Junji Matsui, Tomohiro Matsushima et al. · Vascular Cell · 2014 · 500 citations · Full text

Medicine, Oncology, Pharmacology +16

Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models

Yasuhiro Funahashi, Kiyoshi Okamoto, Yusuke Adachi et al. · Cancer Science · 2014 · 278 citations · Full text

Medicine, Oncology, Pharmacology +17

Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium.

Yasuhiro Funahashi, Naoko Hata Sugi, Taro Semba et al. · PubMed · 2002 · 102 citations

Life Sciences, Cell Biology, Pharmacology +13

An Angiogenesis Inhibitor E7820 Shows Broad-Spectrum Tumor Growth Inhibition in a Xenograft Model

Taro Semba, Yasuhiro Funahashi, Naoto Ono et al. · Clinical Cancer Research · 2004 · 75 citations · Full text

Medicine, Oncology, Pharmacology +17

E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling

Kazuhiko Yamada, Yusaku Hori, Satoshi Inoue et al. · Cancer Research · 2021 · 61 citations · Full text

Medicine, Oncology, Pharmacology +16