Yusaku Hori

Lenvatinib plus anti-PD-1 antibody combination treatment activates CD8+ T cells through reduction of tumor-associated macrophage and activation of the interferon pathway

Yu Kato, Kimiyo Tabata, Takayuki Kimura et al. · PLoS ONE · 2019 · 442 citations · Full text

Flow Cytometric Analysis, Antitumor Activity, Immunology +25

Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1‐6 hepatocellular carcinoma model

Takayuki Kimura, Yu Kato, Yoichi Ozawa et al. · Cancer Science · 2018 · 327 citations · Full text

E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling

Kazuhiko Yamada, Yusaku Hori, Satoshi Inoue et al. · Cancer Research · 2021 · 57 citations · Full text

Lenvatinib mesilate (LEN) enhanced antitumor activity of a PD-1 blockade agent by potentiating Th1 immune response

Yu Kato, Xiaoyi Bao, S. Macgrath et al. · Annals of Oncology · 2016 · 42 citations

Cancer Immunosurveillance, Th1 Immune Response, Medicine +8

Functional Characterization of VEGF- and FGF-induced Tumor Blood Vessel Models in Human Cancer Xenografts

Yusaku Hori, Ken Ito, Shusei Hamamichi et al. · Anticancer Research · 2017 · 34 citations · Full text