Kimiyo Tabata

Lenvatinib plus anti-PD-1 antibody combination treatment activates CD8+ T cells through reduction of tumor-associated macrophage and activation of the interferon pathway

Yu Kato, Kimiyo Tabata, Takayuki Kimura et al. · PLoS ONE · 2019 · 442 citations · Full text

Flow Cytometric Analysis, Antitumor Activity, Immunology +25

Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1‐6 hepatocellular carcinoma model

Takayuki Kimura, Yu Kato, Yoichi Ozawa et al. · Cancer Science · 2018 · 327 citations · Full text

Lenvatinib mesilate (LEN) enhanced antitumor activity of a PD-1 blockade agent by potentiating Th1 immune response

Yu Kato, Xiaoyi Bao, S. Macgrath et al. · Annals of Oncology · 2016 · 42 citations

Cancer Immunosurveillance, Th1 Immune Response, Medicine +8

Abstract A92: Effects of lenvatinib on tumor-associated macrophages enhance antitumor activity of PD-1 signal inhibitors

Yu Kato, Kimiyo Tabata, Yusaku Hori et al. · Molecular Cancer Therapeutics · 2015 · 16 citations

Tumor-associated Macrophages, Immunology, Immunoediting +20

Selective tissue factor/factor VIIa Inhibitor, ER-410660, and its prodrug, E5539, have anti-venous and anti-arterial thrombotic effects with a low risk of bleeding

Tadashi Nagakura, Kimiyo Tabata, Kazunobu Kira et al. · Thrombosis Research · 2013 · 13 citations

Thrombosis, Venous Thrombosis, Cardiovascular Disease +13