S.H. Capetta

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

Antonia F. Stepan, Chakrapani Subramanyam, Ivan Efremov et al. · Journal of Medicinal Chemistry · 2012 · 412 citations · Full text

Metabolism-Directed Design of Oxetane-Containing Arylsulfonamide Derivatives as γ-Secretase Inhibitors

Antonia F. Stepan, Kapil Karki, W. Scott McDonald et al. · Journal of Medicinal Chemistry · 2011 · 106 citations · Full text

Chemical Biology, Experimental Pharmacology, Pharmaceutical Chemistry +16

Discovery and Optimization of a Novel Spiropyrrolidine Inhibitor of β-Secretase (BACE1) through Fragment-Based Drug Design

Ivan Efremov, F.F. Vajdos, Kris A. Borzilleri et al. · Journal of Medicinal Chemistry · 2012 · 63 citations · Full text

Pharmaceutical Science, Drug Target, Novel Spiropyrrolidine Inhibitor +21

Use of Ag(II) as a removable template in porphyrin chemistry: diol cleavage products of [meso-tetraphenyl-2,3-cis-diolchlorinato]silver(II)

Jason R. McCarthy, Patricia J. Melfi, S.H. Capetta et al. · Tetrahedron · 2003 · 52 citations

Inorganic Chemistry, Chemical Engineering, Removable Template +10