J. Bryan Iorgulescu

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

Derin B. Keskin, Annabelle Anandappa, Jing Sun et al. · Nature · 2018 · 1.4K citations · Full text

Neuro-oncology, Tumor Immunology, Cancer Immunosurveillance +10

Mechanisms and therapeutic implications of hypermutation in gliomas

Mehdi Touat, Yvonne Y. Li, Adam N. Boynton et al. · Nature · 2020 · 661 citations · Full text

Neuro-oncology, Medicine, Therapeutic Implications +5

Local disease control for spinal metastases following “separation surgery” and adjuvant hypofractionated or high-dose single-fraction stereotactic radiosurgery: outcome analysis in 186 patients

Ilya Laufer, J. Bryan Iorgulescu, Talia Chapman et al. · Journal of Neurosurgery Spine · 2013 · 509 citations · Full text

Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

Zhuting Hu, Donna Leet, Rosa Lundbye Allesøe et al. · Nature Medicine · 2021 · 482 citations · Full text

Vaccination, Tumor Immunology, Epitope Spreading +11

Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

Romain Guièze, Vivian M. Liu, Daniel Rosebrock et al. · Cancer Cell · 2019 · 348 citations · Full text

Lymphoid Neoplasia, Mitochondrial Function, Medicine +9