Concepedia

Isabelle Heit

IH

6

Publications

148

Citations

6

H-Index

2001

Active since

Affiliations

National Cancer Institute(Current)

Johannes Gutenberg University Mainz

Isabelle Heit is an author at National Cancer Institute specializing in medicine, medicinal chemistry, and drug discovery.

Top concepts

MedicineCell BiologyPharmacologyDrug DiscoveryCell PhysiologyMedicinal ChemistryCellular BiochemistryCell GrowthDermatologyDrug Design

Publications per year

2001–2011

6

Publications

6

Critical role of novel Thr‐219 autophosphorylation for the cellular function of PKCθ in T lymphocytes

Niκolaus Thuille, Isabelle Heit, Friedrich Fresser et al. · The EMBO Journal · 2005 · 52 citations · Full text

Involvement of protein kinase Cδ in contact-dependent inhibition of growth in human and murine fibroblasts

Isabelle Heit, Raimund Wieser, Thomas Herget et al. · Oncogene · 2001 · 35 citations

Signal Transduction, Developmental Biology, Contact-dependent Inhibition +15

Identification of potent ITK inhibitors through focused compound library design including structural information

Matthias Herdemann, Isabelle Heit, Frank-Uwe Bosch et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 18 citations · Full text

Molecular Docking, Medicinal Chemistry, Compound Library Design +12

Optimisation of ITK inhibitors through successive iterative design cycles

Matthias Herdemann, Alexander Weber, Jérôme Jonveaux et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 15 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +5

Rottlerin Induces a Transformed Phenotype in Human Keratinocytes

Cornelia Dietrich, Nicolas Gumpert, Isabelle Heit et al. · Biochemical and Biophysical Research Communications · 2001 · 15 citations

Cell Division, Cutaneous Biology, Transformed Phenotype +5

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