Rottlerin Induces a Transformed Phenotype in Human Keratinocytes

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

Petra Boukamp, R T Petrussevska, Dirk Breitkreutz et al. · The Journal of Cell Biology · 1988 · 4.1K citations · Full text

Skin Development, Cell Division, Cutaneous Biology +11

Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion.

Jürgen Behrens, M. Mareel, Frans van Roy et al. · The Journal of Cell Biology · 1989 · 949 citations · Full text

Cell Adhesion, Immunology, Pathology +18

Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.

Jürgen Behrens, L. Vakaet, Robert R. Friis et al. · The Journal of Cell Biology · 1993 · 907 citations · Full text

Cell Adhesion, Cell Proliferation, Cytoskeleton +19

Rottlerin, a Novel Protein Kinase Inhibitor

Michael Gschwendt, H.-J. Müller, Kirsten Kielbassa et al. · Biochemical and Biophysical Research Communications · 1994 · 848 citations

Protein Function, Receptor Tyrosine Kinase, Autophagy +5

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

Vania Braga, Laura M. Machesky, Alan Hall et al. · The Journal of Cell Biology · 1997 · 762 citations · Full text