Thorsten E. Fisher

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

Daria J. Hazuda, Neville J. Anthony, Robert Gomez et al. · Proceedings of the National Academy of Sciences · 2004 · 332 citations · Full text

Hiv-1 Integrase, Immunology, Cell Culture +17

Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

Linghang Zhuang, John Wai, Mark W. Embrey et al. · Journal of Medicinal Chemistry · 2003 · 266 citations · Full text

Hiv-1 Integrase, Biochemistry, Medicine +14

4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells

John Wai, Melissa S. Egbertson, Linda S. Payne et al. · Journal of Medicinal Chemistry · 2000 · 187 citations · Full text

Hiv-1 Integrase, Viral Replication, Immunology +17

2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors

Walfred S. Saari, J. M. HOFFMAN, John Wai et al. · Journal of Medicinal Chemistry · 1991 · 107 citations · Full text

Pharmacotherapy, Antiviral Drug, Pre-clinical Pharmacology +17

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogs of 3-aminopyridin-2(1H)-one

Walfred S. Saari, John Wai, Thorsten E. Fisher et al. · Journal of Medicinal Chemistry · 1992 · 94 citations · Full text