David Westover

Quantifying Drug Combination Synergy along Potency and Efficacy Axes

Christian T. Meyer, David J. Wooten, B. Bishal Paudel et al. · Cell Systems · 2019 · 215 citations

Drug Combination Synergy, Substance Abuse, Addiction +4

SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer

Eiki Ichihara, David Westover, Catherine B. Meador et al. · Cancer Research · 2017 · 141 citations

On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation

Benjamin P. Brown, Yunkai Zhang, David Westover et al. · Clinical Cancer Research · 2019 · 107 citations · Full text

Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids

Anna E. Vilgelm, Kensey Bergdorf, Melissa M. Wolf et al. · iScience · 2020 · 75 citations · Full text

Medicine, Tumor Targeting, Organoid Models +6

FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance

David Westover, Xiang Ling, Hong Lam et al. · Molecular Cancer · 2015 · 68 citations · Full text