Lear E. Brace

Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction

Evandro Fei Fang, Morten Scheibye‐Knudsen, Lear E. Brace et al. · Cell · 2014 · 710 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits

Christopher Hine, Eylul Harputlugil, Yue Zhang et al. · Cell · 2014 · 564 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +8

Mutations in the <i>DDR2</i> Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

Peter S. Hammerman, Martin L. Sos, Alex H. Ramos et al. · Cancer Discovery · 2011 · 472 citations · Full text

Medicine, Genetics, Oncology +16

Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production

Alban Longchamp, Teodelinda Mirabella, Alessandro Arduini et al. · Cell · 2018 · 330 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Increased oxidative phosphorylation in response to acute and chronic DNA damage

Lear E. Brace, Sarah Vose, Kristopher J. Stanya et al. · npj Aging and Mechanisms of Disease · 2016 · 119 citations · Full text

Life Sciences, Molecular Biology, Toxicology +17