Juliann Chmielecki

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

Zachary R. Chalmers, Caitlin Connelly, David Fabrizio et al. · Genome Medicine · 2017 · 3.7K citations · Full text

Medicine, Cancer Biology, Oncology +17

Anchored multiplex PCR for targeted next-generation sequencing

Zongli Zheng, Matthew Liebers, Boryana Zhelyazkova et al. · Nature Medicine · 2014 · 917 citations · Full text

Life Sciences, Biology, Molecular Biology +9

Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors

Garrett M. Frampton, Siraj M. Ali, Mark R. Rosenzweig et al. · Cancer Discovery · 2015 · 796 citations · Full text

Medicine, Molecular Genetics, Oncology +16

Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors

Jack F. Shern, Li Chen, Juliann Chmielecki et al. · Cancer Discovery · 2014 · 777 citations · Full text

Medicine, Molecular Genetics, Oncology +17

Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation

Geoffrey R. Oxnard, Maria E. Arcila, Camelia S. Sima et al. · Clinical Cancer Research · 2010 · 625 citations · Full text

Medicine, Oncology, Pharmacology +17