Kelvin Sham

Synthesis of Aromatic Heterocycles via Palladium-Catalyzed Annulation of Internal Alkynes

Richard C. Larock, Mark J. Doty, Kelvin Sham · The Journal of Organic Chemistry · 1995 · 288 citations

Chemical Engineering, Engineering, Heterocyclic +10

First X-ray Cocrystal Structure of a Bacterial FabH Condensing Enzyme and a Small Molecule Inhibitor Achieved Using Rational Design and Homology Modeling

R. A. DAINES, Israil Pendrak, Kelvin Sham et al. · Journal of Medicinal Chemistry · 2002 · 72 citations

X-ray Crystallography, Biochemistry, Biomolecular Structure Prediction +15

Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold

Brad Herberich, Guoqiang Cao, Partha Chakrabarti et al. · Journal of Medicinal Chemistry · 2008 · 57 citations · Full text

Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

Bryan D. Moyer, Justin K. Murray, Joseph Ligutti et al. · PLoS ONE · 2018 · 49 citations · Full text

Pharmacological Characterization, Molecular Biology, Molecular Pain +17

Discovery of Tarantula Venom-Derived Na_V1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Bin Wu, Justin K. Murray, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2018 · 31 citations · Full text