Bitao Huo

Metabolomic differentiation of benign vs malignant pulmonary nodules with high specificity via high-resolution mass spectrometry analysis of patient sera

Yao Yao, Xueping Wang, Jian Guan et al. · Nature Communications · 2023 · 50 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Design and Synthesis of Dual EZH2/BRD4 Inhibitors to Target Solid Tumors

Zhirong Guo, Yameng Sun, Liyun Liang et al. · Journal of Medicinal Chemistry · 2022 · 48 citations · Full text

Medicine, Oncology, Pharmacology +13

Gut Microbiome-Generated Phenylacetylglutamine from Dietary Protein is Associated with Crohn’s Disease and Exacerbates Colitis in Mouse Model Possibly via Platelet Activation

Rui Feng, Zhenyi Tian, Ren Mao et al. · Journal of Crohn s and Colitis · 2023 · 41 citations

Life Sciences, Immunology, Nutritional Sciences +17

Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity

Yongxiang Liu, Zifeng Wang, Huan Jin et al. · Cell Reports · 2024 · 21 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Cancer cell-intrinsic biosynthesis of itaconate promotes tumor immunogenicity

Zining Wang, Lei Cui, Bitao Huo et al. · The EMBO Journal · 2024 · 17 citations · Full text

Medicine, Immunology, Oncology +17