Sergio Crespo‐Garcia

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

François Binet, Gaël Cagnone, Sergio Crespo‐Garcia et al. · Science · 2020 · 272 citations

Ocular Disease, Immunology, Retinal Therapies +18

Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition

Sergio Crespo‐Garcia, Pamela R. Tsuruda, Agnieszka Dejda et al. · Cell Metabolism · 2021 · 173 citations · Full text

Ocular Disease, Angiogenesis, Ophthalmology +10

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation

Masayuki Hata, Elisabeth M. M. A. Andriessen, Maki Hata et al. · Science · 2023 · 155 citations

Innate Immune System, Immunology, Cell Death +22

NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy

Khalil Miloudi, Malika Oubaha, Catherine Ménard et al. · Proceedings of the National Academy of Sciences · 2019 · 86 citations · Full text

Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results

Sergio Crespo‐Garcia, Frédérik Fournier, Roberto Diaz-Marin et al. · Nature Medicine · 2024 · 74 citations

Regenerative Medicine, Diabetic Retinopathy, Ocular Disease +10