Mary‐Margaret O'Donnell

Acylguanidine inhibitors of β-secretase: Optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets

Derek C. Cole, Joseph R. Stock, Rajiv Chopra et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 70 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +11

Incorporation of carbohydrates and peptides into large triazine-based screening libraries using automated parallel synthesis

Gary Gustafson, Carmen M. Baldino, Mary‐Margaret O'Donnell et al. · Tetrahedron · 1998 · 57 citations

Combinatorial Chemistry, Medicinal Chemistry, Automated Parallel Synthesis +10

Acylguanidine inhibitors of β-secretase: Optimization of the pyrrole ring substituents extending into the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si2.gif" overflow="scroll"><mml:mrow><mml:msubsup><mml:mrow><mml:mi mathvariant="bold">S</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn></mml:mrow><mml:mrow><mml:mo>′</mml:mo></mml:mrow></mml:msubsup></mml:mrow></mml:math> substrate binding pocket

Lee D. Jennings, Derek C. Cole, Joseph R. Stock et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 36 citations

The design and preparation of metabolically protected new arylpiperazine 5-HT1A ligands

Manish Tandon, Mary‐Margaret O'Donnell, Alex Porte et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 31 citations · Full text

Biochemistry, Medicine, Rational Drug Design +3

Synthesis of 1,2-disubstituted-3-alkylidenylpyrrolidines via a one-pot three-component reaction

Wenwei Huang, Mary‐Margaret O'Donnell, Grace Bi et al. · Tetrahedron Letters · 2004 · 13 citations

One-pot Three-component Reaction, Organic Chemistry, Stereoselective Synthesis +2