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The design and preparation of metabolically protected new arylpiperazine 5-HT1A ligands

Manish Tandon, Mary‐Margaret O'Donnell, Alex Porte, David Vensel, Donglaï Yang, Rocio Palma, Alan Beresford, Mark A. Ashwell

Bioorganic & Medicinal Chemistry Letters · 2004 · 31 citations · 12 references

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12

Theoretical studies on cytochrome P-450 mediated hydroxylation: a predictive model for hydrogen atom abstractions

Kenneth R. Korzekwa, Jeffery P. Jones, James R. Gillette · Journal of the American Chemical Society · 1990 · 139 citations

, , +17

Computational Models for Cytochrome P450: A Predictive Electronic Model for Aromatic Oxidation and Hydrogen Atom Abstraction

Jeffrey P. Jones, Michael M. Mysinger, Kenneth R. Korzekwa · Drug Metabolism and Disposition · 2002 · 121 citations

, , +16

Metabolism of the antianxiety drug buspirone in human subjects.

Hemant K. Jajoo, Robert F. Mayol, John A. Labudde et al. · Drug Metabolism and Disposition · 1989 · 80 citations

, , +13

Psychosedative agents. 2. 8-(4-Substituted 1-piperazinylalkyl)-8-azaspiro[4.5]decane-7,9-diones

Yaohua Wu, James W. Rayburn, Hadley Ferguson et al. · Journal of Medicinal Chemistry · 1972 · 75 citations

, , +5

Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 2. Three-Dimensional Quantitative Structure−Activity Relationships of Hydantoin−Phenylpiperazine Derivatives with Affinity for 5-HT<sub>1A</sub> and α<sub>1</sub> Receptors. A Comparison of CoMFA Models

María L. López-Rodrı́guez, M. Luisa Rosado, Bellinda Benhamú et al. · Journal of Medicinal Chemistry · 1997 · 64 citations · Full text

, , +17