Jean-François Spinella

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

Irène Baccelli, Yves Gareau, Bernhard Lehnertz et al. · Cancer Cell · 2019 · 255 citations · Full text

Hematological Malignancy, Biochemistry, Natural Sciences +9

Genetic characterization of ABT-199 sensitivity in human AML

Richard Bisaillon, Céline Moison, Clarisse Thiollier et al. · Leukemia · 2019 · 91 citations

Human Aml, Allelic Variant, Medicine +6

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex

Jalila Chagraoui, Simon Girard, Jean-François Spinella et al. · Cell stem cell · 2021 · 88 citations · Full text

Clr3-kbtbd4 Complex, Chromatin, Chromatin Remodeling +10

High frequency of germline <i>RUNX1</i> mutations in patients with<i> RUNX1</i>-mutated AML

Laura Simon, Jean-François Spinella, Chi‐Yuan Yao et al. · Blood · 2020 · 86 citations · Full text

SNooPer: a machine learning-based method for somatic variant identification from low-pass next-generation sequencing

Jean-François Spinella, Pamela Mehanna, Ramón Vidal et al. · BMC Genomics · 2016 · 68 citations · Full text