Jean-François Spinella

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

Irène Baccelli, Yves Gareau, Bernhard Lehnertz et al. · Cancer Cell · 2019 · 262 citations · Full text

Medicine, Oncology, Pharmacology +12

Genetic characterization of ABT-199 sensitivity in human AML

Richard Bisaillon, Céline Moison, Clarisse Thiollier et al. · Leukemia · 2019 · 94 citations

Life Sciences, Genetics, Molecular Genetics +5

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex

Jalila Chagraoui, Simon Girard, Jean-François Spinella et al. · Cell stem cell · 2021 · 93 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +6

Whole-Exome Sequencing Reveals a Rapid Change in the Frequency of Rare Functional Variants in a Founding Population of Humans

Ferrán Casals, Alan Hodgkinson, Julie Hussin et al. · PLoS Genetics · 2013 · 92 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

High frequency of germline <i>RUNX1</i> mutations in patients with<i> RUNX1</i>-mutated AML

Laura Simon, Jean-François Spinella, Chi‐Yuan Yao et al. · Blood · 2020 · 88 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12