Alessandra Leone

HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT

Francesca Bruzzese, Alessandra Leone, Monia Rocco et al. · Journal of Cellular Physiology · 2010 · 140 citations

Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15

Francesca Bruzzese, Christina Hägglöf, Alessandra Leone et al. · Cancer Research · 2014 · 123 citations

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

Chiara Ciardiello, Alessandra Leone, Paola Lanuti et al. · Journal of Experimental & Clinical Cancer Research · 2019 · 117 citations · Full text

Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models

Stefania Cocco, Alessandra Leone, Maria Serena Roca et al. · Journal of Translational Medicine · 2022 · 109 citations · Full text

Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway

Alessandra Leone, Maria Serena Roca, Chiara Ciardiello et al. · Free Radical Biology and Medicine · 2015 · 82 citations

C-myc-nrf2-keap1 Pathway, Signal Transduction, Signaling Pathway +8