Francesca Bruzzese

HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT

Francesca Bruzzese, Alessandra Leone, Monia Rocco et al. · Journal of Cellular Physiology · 2010 · 140 citations

Medicine, Oncology, Pharmacology +17

Critical role of both p27^KIP1and p21^CIP1/WAF1 in the antiproliferative effect of ZD1839 (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells

Elena Di Gennaro, Marcella Barbarino, Francesca Bruzzese et al. · Journal of Cellular Physiology · 2003 · 131 citations

Medicine, Oncology, Pharmacology +17

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

Chiara Ciardiello, Alessandra Leone, Paola Lanuti et al. · Journal of Experimental & Clinical Cancer Research · 2019 · 126 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15

Francesca Bruzzese, Christina Hägglöf, Alessandra Leone et al. · Cancer Research · 2014 · 124 citations

Medicine, Cancer Biology, Oncology +17

Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models

Stefania Cocco, Alessandra Leone, Maria Serena Roca et al. · Journal of Translational Medicine · 2022 · 116 citations · Full text

Medicine, Oncology, Pharmacology +17